Step-by-step laboratory protocols for transgenesis and gene editing enable consistent experimental results
Includes detailed information on genotyping and validation to ensure successful gene targeting
Covers both traditional and CRISPR-based methods for versatile research applications
Troubleshooting tips and pitfalls avoidances help researchers refine their experimental approach
Written for the Methods in Molecular Biology series, ensuring authoritative and practical content
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Transgenesis: Methods and Protocols Saunders, Thomas L. This detailed volume focuses on genotyping and validation in addition to information on how to produce gene edited cells and animals for research. Future advances in biomedical research will benefit greatly from the use of precise gene targeting of transgenes in the genome as CRISPR