My son has tried 6 other formulas in the 2m hes been alive. He was diagnosed with reflux at 6 weeks old and was on Kendamil goat but his doctor wanted him on a hypoallergenic formula and switched him to Similac alimentum. It made his reflux worse, even with increasing the meds. His pediatrician suggested trying a formula from Europe if I was comfortable shipping something like that to the states and at this point I was willing to try literally anything. She suggested HiPP HA Combitok But I also realized that they had an anti-reflux formula. So I said what the hell. Let's try both. I ordered one box of the combitok And two boxes of the anti reflux and from the very first bottle there has been a significant difference in his eating habits. My biggest regret is not switching him to a European formula when he was taken off kenda goat for Similac alimentum. We will definitely be ordering more!!